Search on: METHYL CPG BINDING DOMAIN 
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Descriptor English:   Methyl CpG Binding Domain 
Descriptor Spanish:   Dominio de Unión a CpG-Metil 
Descriptor Portuguese:   Domínio de Ligação a CpG Metilada 
Synonyms English:   Methyl CpG DNA Binding Domain  
Tree Number:   G02.111.570.820.709.275.750.438
Definition English:   A protein domain of about 70 amino acids in length that folds into a sandwich structure consisting of a beta sheet, alpha helix, and C-terminal hairpin loop which forms a hydrophobic methylated-DNA binding patch. It binds to methylated CPG ISLANDS in eukaryotes and occurs with other DNA and CHROMATIN binding domains such as AT-HOOK MOTIFS in eukaryotic DNA BINDING PROTEINS. 
See Related English:   DNA Methylation
 
History Note English:   2017 
Allowable Qualifiers English:  
DE drug effects GE genetics
IM immunology PH physiology
RE radiation effects  
Record Number:   56741 
Unique Identifier:   D000070593 

Occurrence in VHL:
 

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